Crystal structure of akuammicine, an indole alkaloid from Catharanthus roseus

Yahyazadeh, Mahdi; Jerz, Gerold; Selmar, Dirk; Winterhalter, Peter; Jones, Peter, G.

doi:10.1107/S2056989017014529

Article / Chapter Mon Nov 13 2017 CC BY 4.0

published

Crystal structure of akuammicine, an indole alkaloid from Catharanthus roseus

Yahyazadeh, Mahdi ; Jerz, Gerold ; Selmar, Dirk ; Winterhalter, Peter ; Jones, Peter G.

The title compound, C20H22N2O2, an alkaloid isolated from the Madagascar periwinkle, crystallizes in P1 with two independent but closely similar molecules in the unit cell. The molecules are linked into pairs by two N—H⋯O=C hydrogen bonds. The absolute configuration was confirmed by anomalous dispersion effects as S at the 3 and 15 positions, and R at the 7 position.